The MathDox Player can use a Computer Algebra System (CAS) to evaluate mathematical expressions. An OpenMath Phrasebook is used to access the CAS with OpenMath queries. Phrasebooks for Maxima, GAP and Mathematica have been included in the MathDox Player, and need therefore not be installed. However, each phrasebook depends on a so-called 'service' program. The service program enables communication between an OpenMath Phrasebook and a CAS, and should therefore be installed and running before using a CAS from the MathDox Player.

The Maxima Service, GAP Service and Mathematica Service can all be downloaded from the mathdox.org website. Installation instructions are available in the INSTALL file inside the downloaded package.